Is Hexyl Formate safe in cosmetics?
Hexyl Formate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hexyl Formate
Also known as: BRN 1701629, EINECS 211-087-1, FEMA No. 2570, n-Hexyl formate, Hexyl methanoate (+3 more)
INCI: HEXYL FORMATE
Hexyl Formate (CAS 629-33-4) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (fruity ester); FDA-listed flavoring agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 629-33-4 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient (fruity ester); FDA-listed flavoring agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
hexyl formate
InChIKey
OUGPMNMLWKSBRI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — listed as GRAS flavoring agent (21 CFR 182.60 category); no specific cosmetic restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexyl Formate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
120
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
HEXYL FORMATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Hexyl Formate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
BRN 1701629
EINECS 211-087-1
FEMA No. 2570
n-Hexyl formate
Hexyl methanoate
n-Hexyl methanoate
NSC 4780
UNII-9GPU7PGV1G
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
HEXYL FORMATE
ChEMBL ID
CHEMBL2270391
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
HEXYL FORMATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Hexyl Formate allowed in the EU?
Hexyl Formate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexyl Formate do in cosmetics?
Hexyl Formate functions as: Fragrance ingredient (fruity ester); FDA-listed flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 629-33-4.
Is Hexyl Formate used outside cosmetics?
Hexyl Formate also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexyl Formate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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