Methylenedioxyphenyl Dihydroxybenzamide

INCI: METHYLENEDIOXYPHENYL DIHYDROXYBENZAMIDE

CAS Number
Not widely listed in major databases; limited CosIng entry
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted under current FDA cosmetic regulations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited published toxicological data; the methylenedioxyphenyl moiety (piperonal-type scaffold) is generally well tolerated, and dihydroxybenzamide structures are associated with antioxidant activity. The dihydroxybenzamide portion suggests chelating and radical-scavenging capability, while the methylenedioxyphenyl group may enhance skin penetration and stability

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Concern Level: High

Frequently Asked Questions

Is Methylenedioxyphenyl Dihydroxybenzamide safe in cosmetics?

Very limited published toxicological data; the methylenedioxyphenyl moiety (piperonal-type scaffold) is generally well tolerated, and dihydroxybenzamide structures are associated with antioxidant activity. The dihydroxybenzamide portion suggests chelating and radical-scavenging capability, while the methylenedioxyphenyl group may enhance skin penetration and stability The EU classifies Methylenedioxyphenyl Dihydroxybenzamide as "permitted". Safety rating: MODERATE.

Is Methylenedioxyphenyl Dihydroxybenzamide allowed in the EU?

Methylenedioxyphenyl Dihydroxybenzamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylenedioxyphenyl Dihydroxybenzamide do in cosmetics?

Methylenedioxyphenyl Dihydroxybenzamide functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: Not widely listed in major databases; limited CosIng entry.

What is the Margin of Safety for Methylenedioxyphenyl Dihydroxybenzamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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