Methylinositol

INCI: METHYLINOSITOL

CAS Number
484-68-4
Function
Skin Conditioning, Humectant - based on structural analogy to inositol
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No significant cosmetic safety concerns documented; has been investigated in clinical trials for dementia and Alzheimer's disease, suggesting good systemic tolerability. Also known as ononitol (+); a methylated derivative of inositol (cyclohexanehexol); inositol-class ingredients function as antistatic agents, hair conditioning agents, and humectants; the methyl substitution modifies solubility and skin-penetration characteristics compared to parent inositol

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Concern Level: Moderate

Frequently Asked Questions

Is Methylinositol safe in cosmetics?

No significant cosmetic safety concerns documented; has been investigated in clinical trials for dementia and Alzheimer's disease, suggesting good systemic tolerability. Also known as ononitol (+); a methylated derivative of inositol (cyclohexanehexol); inositol-class ingredients function as antistatic agents, hair conditioning agents, and humectants; the methyl substitution modifies solubility and skin-penetration characteristics compared to parent inositol The EU classifies Methylinositol as "permitted". Safety rating: MODERATE.

Is Methylinositol allowed in the EU?

Methylinositol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylinositol do in cosmetics?

Methylinositol functions as: Skin Conditioning, Humectant - based on structural analogy to inositol. It is classified as a cosmetic ingredient in our database. CAS number: 484-68-4.

What is the Margin of Safety for Methylinositol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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