Moderate Cosmetic Ingredient

Minoxidil Hyaluronamide

INCI: MINOXIDIL HYALURONAMIDE

CAS Number
None assigned per CosIng
Function
Humectant
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Minoxidil is FDA-approved as an OTC drug (for hair regrowth). A hyaluronamide conjugate used in a cosmetic context would likely face FDA scrutiny regarding drug/cosmetic classification. No specific FDA prohibition as a cosmetic ingredient, but drug-cosmetic boundary issues apply.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Minoxidil is a potent vasodilator - systemic absorption risks include hypotension, tachycardia, and fluid retention. The hyaluronic acid conjugation may modulate penetration but safety data for this specific conjugate is limited. Novel hybrid ingredient combining minoxidil's vasodilatory/hair growth properties with hyaluronic acid's humectant capacity. Relatively new entry in CosIng; very limited commercial use data. This is a synthetic/biotech-derived ingredient (not animal-derived from mink)

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Concern Level: Moderate

Frequently Asked Questions

Is Minoxidil Hyaluronamide safe in cosmetics?

Minoxidil is a potent vasodilator - systemic absorption risks include hypotension, tachycardia, and fluid retention. The hyaluronic acid conjugation may modulate penetration but safety data for this specific conjugate is limited. Novel hybrid ingredient combining minoxidil's vasodilatory/hair growth properties with hyaluronic acid's humectant capacity. Relatively new entry in CosIng; very limited commercial use data. This is a synthetic/biotech-derived ingredient (not animal-derived from mink) The EU classifies Minoxidil Hyaluronamide as "permitted". Safety rating: MODERATE.

Is Minoxidil Hyaluronamide allowed in the EU?

Minoxidil Hyaluronamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Minoxidil Hyaluronamide do in cosmetics?

Minoxidil Hyaluronamide functions as: Humectant. It is classified as a cosmetic ingredient in our database. CAS number: None assigned per CosIng.

What is the Margin of Safety for Minoxidil Hyaluronamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Minoxidil Hyaluronamide compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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