Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Mixed Terpenes. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 50 ppm | 1991 | mouse | inhalation | REACH |
| NOAEL | 435.8 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 250 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 25 ppm | 1991 | rat | inhalation | REACH |
| NOAEL | 1500 ppm | oral | rat | oral | REACH |
Expert Verdict
Potential skin sensitization and irritation, particularly from oxidized terpene fractions. Peroxide value of the terpene mixture must be kept low to minimize sensitization risk. Volatile organic compound (VOC) concerns in certain jurisdictions. A mixture of hydrocarbons distilled from plants and trees such as pine and citrus. Comprises terpenes, sesquiterpenes, diterpenes, and polyterpenes. Acts primarily as a natural solvent alternative
Regulatory Flags
Frequently Asked Questions
Is Mixed Terpenes safe in cosmetics?
Potential skin sensitization and irritation, particularly from oxidized terpene fractions. Peroxide value of the terpene mixture must be kept low to minimize sensitization risk. Volatile organic compound (VOC) concerns in certain jurisdictions. A mixture of hydrocarbons distilled from plants and trees such as pine and citrus. Comprises terpenes, sesquiterpenes, diterpenes, and polyterpenes. Acts primarily as a natural solvent alternative The EU classifies Mixed Terpenes as "restricted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.
Is Mixed Terpenes allowed in the EU?
Mixed Terpenes EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mixed Terpenes do in cosmetics?
Mixed Terpenes functions as: Solvent - dissolves other substances. It is classified as a cosmetic ingredient in our database. CAS number: 68956-56-9.
What is the Margin of Safety for Mixed Terpenes?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Mixed Terpenes?
The NOAEL (No Observed Adverse Effect Level) for Mixed Terpenes is 50 ppm based on a inhalation study via 1991 route in mouse. A total of 5 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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