Regulatory Status
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Safety Data
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Expert Verdict
Morus bombycis root extract is permitted in EU as a skin conditioning ingredient with no Annex II, III, V, or VI restrictions, and permitted in the US as a general cosmetic ingredient with no FDA restrictions, though claims of hyperpigmentation treatment may trigger drug classification; safety profile is favorable based on in vitro cytotoxicity and acute oral toxicity data, but key data gaps exist including dermal absorption, margin of safety calculation, genotoxicity, reproductive toxicity, and formal sensitization studies.
Regulatory Flags
Frequently Asked Questions
Is Morus Bombycis Root Extract safe in cosmetics?
Morus bombycis root extract is permitted in EU as a skin conditioning ingredient with no Annex II, III, V, or VI restrictions, and permitted in the US as a general cosmetic ingredient with no FDA restrictions, though claims of hyperpigmentation treatment may trigger drug classification; safety profile is favorable based on in vitro cytotoxicity and acute oral toxicity data, but key data gaps exist including dermal absorption, margin of safety calculation, genotoxicity, reproductive toxicity, and formal sensitization studies. The EU classifies Morus Bombycis Root Extract as "permitted". Safety rating: GOOD.
Is Morus Bombycis Root Extract allowed in the EU?
Morus Bombycis Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Morus Bombycis Root Extract do in cosmetics?
Morus Bombycis Root Extract functions as: Skin conditioning, skin brightening/depigmenting, antioxidant. It is classified as a Active Ingredient in our database. CAS number: 85251-65-6.
What is the Margin of Safety for Morus Bombycis Root Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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