Regulatory Status
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Safety Data
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Dermal Penetration Profile
Skin absorption and penetration characteristics of Bakuchiol, relevant to systemic exposure and MoS calculations.
Source: Int J Cosmet Sci 2014
Expert Verdict
Plant-derived retinoid alternative from Psoralea corylifolia with dual value in brightening formulations through modest direct tyrosinase inhibition and retinol-like keratinocyte turnover promotion. A 2024 systematic review of 15 clinical trials confirmed efficacy for post-inflammatory hyperpigmentation, aging, and acne with good tolerability. Bakuchiol functions best as a complementary ingredient alongside primary tyrosinase inhibitors rather than as a standalone brightening active. Key advantages versus retinoids include no photosensitization, pregnancy compatibility, and exemption from EU 2024/996 Vitamin A concentration restrictions, making it excellent for sensitive skin and darker phototypes.
Regulatory Flags
Frequently Asked Questions
Is Bakuchiol safe in cosmetics?
Plant-derived retinoid alternative from Psoralea corylifolia with dual value in brightening formulations through modest direct tyrosinase inhibition and retinol-like keratinocyte turnover promotion. A 2024 systematic review of 15 clinical trials confirmed efficacy for post-inflammatory hyperpigmentation, aging, and acne with good tolerability. Bakuchiol functions best as a complementary ingredient alongside primary tyrosinase inhibitors rather than as a standalone brightening active. Key advantages versus retinoids include no photosensitization, pregnancy compatibility, and exemption from EU 2024/996 Vitamin A concentration restrictions, making it excellent for sensitive skin and darker phototypes. The EU classifies Bakuchiol as "permitted". Safety rating: EXCELLENT.
Is Bakuchiol allowed in the EU?
Bakuchiol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bakuchiol do in cosmetics?
Bakuchiol functions as: Retinol functional analog (non-retinoid); promotes epidermal keratinocyte turnover and melanin dispersal; modest tyrosinase inhibitor; antioxidant; anti-inflammatory; acts on retinoid receptors without being a retinoid molecule. It is classified as a Active Ingredient in our database. CAS number: 10309-37-2.
What is the Margin of Safety for Bakuchiol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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