N-ACETYL DIHYDROSPHINGOSINE

Also known as: UNII-ZZK8X1CR0R, Acetamide, N-((1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl)-, Acetamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (R-(R*,S*))-, Acetamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, d-erythro-, D-erythro-1,3-Dihydroxy-2-acetamidooctadecane (+7 more)

N-ACETYL DIHYDROSPHINGOSINE (CAS 13031-64-6) is a cosmetic cosmetic ingredient functioning as Hair Conditioning, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 13031-64-6 →

Auto-generated CPSR Part A draft with source citations
Function
Hair Conditioning, Skin Conditioning
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C20H41NO3
MW
343.5 g/mol
PubChem CID
6610273
IUPAC Name
N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]acetamide
InChIKey
CRJGESKKUOMBCT-VQTJNVASSA-N

Regulatory Status

EU EU Status permitted
US US Status prohibited
US Notes Allowed; not prohibited or restricted. No CIR safety concerns flagged for ceramide-class ingredients at typical use levels

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for N-ACETYL DIHYDROSPHINGOSINE.

Regulatory Flags

cosing-sourced eu-permitted skin-conditioning hair-conditioning needs-enrichment

Known Synonyms

UNII-ZZK8X1CR0R Acetamide, N-((1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl)- Acetamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (R-(R*,S*))- Acetamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, d-erythro- D-erythro-1,3-Dihydroxy-2-acetamidooctadecane D-erythro-2-Acetamido-1,3-octadecanediol D-erythro-N-Acetylsphinganine dS-N-Acetylsphinganine C2-dihydroceramide N-acetyldihydrosphingosine dihydro-C2-ceramide N-acetylsphinganine

Chemical Function

Softener and conditioner

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
CERAMIDE
ChEMBL ID
CHEMBL155886
Max Phase
2
View full pharmaceutical profile →

Frequently Asked Questions

Is N-ACETYL DIHYDROSPHINGOSINE safe in cosmetics?

N-ACETYL DIHYDROSPHINGOSINE has a safety rating of "GOOD" in our database. EU status: permitted. US status: prohibited.

Is N-ACETYL DIHYDROSPHINGOSINE allowed in the EU?

N-ACETYL DIHYDROSPHINGOSINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does N-ACETYL DIHYDROSPHINGOSINE do in cosmetics?

N-ACETYL DIHYDROSPHINGOSINE functions as: Hair Conditioning, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 13031-64-6.

Is N-ACETYL DIHYDROSPHINGOSINE used outside cosmetics?

N-ACETYL DIHYDROSPHINGOSINE also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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Good Similar safety
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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
N-ACETYLSALICYLOYL PHYTOSPHINGOSINE
Good Browse nearby
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N-ADAMANTANOYL DOPAMINE
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N-ADAMANTANOYL TYRAMINE
Moderate Browse nearby
Antioxidant, Skin Protecting

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