Regulatory Status
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Safety Data
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Expert Verdict
CB1-dependent mechanism—at very high topical concentrations, consider potential for localized cannabinoid receptor effects. Analog of N-palmitoyl ethanolamine (PEA), which has extensive safety data. No oxidation-prone unsaturation. Peer-reviewed data available for read-across.
Frequently Asked Questions
Is N-Palmitoyl Serinol safe in cosmetics?
CB1-dependent mechanism—at very high topical concentrations, consider potential for localized cannabinoid receptor effects. Analog of N-palmitoyl ethanolamine (PEA), which has extensive safety data. No oxidation-prone unsaturation. Peer-reviewed data available for read-across. The EU classifies N-Palmitoyl Serinol as "permitted". Safety rating: GOOD.
Is N-Palmitoyl Serinol allowed in the EU?
N-Palmitoyl Serinol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does N-Palmitoyl Serinol do in cosmetics?
N-Palmitoyl Serinol functions as: Skin conditioning — ceramide analog; stimulates endogenous ceramide production via CB1 receptor. It is classified as a cosmetic ingredient in our database. CAS number: 126127-31-9.
What is the Margin of Safety for N-Palmitoyl Serinol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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