Moderate Cosmetic Ingredient GHS Classified

Neopentyl Glycol Dimethacrylate

INCI: NEOPENTYL GLYCOL DIMETHACRYLATE

CAS Number
2223-82-7
Function
Nail enhancement polymer, film former
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted - CIR reviewed; safe when skin contact avoided

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization.
Routes of Exposure
The substance can be absorbed into the body by inhalation and through the skin.

Expert Verdict

Acute Tox. 3 Dermal; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1; CIR determined safe in nail products when skin contact avoided; requires consumer warnings

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Concern Level: High

Frequently Asked Questions

Is Neopentyl Glycol Dimethacrylate safe in cosmetics?

Acute Tox. 3 Dermal; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1; CIR determined safe in nail products when skin contact avoided; requires consumer warnings The EU classifies Neopentyl Glycol Dimethacrylate as "permitted". Safety rating: MODERATE.

Is Neopentyl Glycol Dimethacrylate allowed in the EU?

Neopentyl Glycol Dimethacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Neopentyl Glycol Dimethacrylate do in cosmetics?

Neopentyl Glycol Dimethacrylate functions as: Nail enhancement polymer, film former. It is classified as a cosmetic ingredient in our database. CAS number: 2223-82-7.

What is the Margin of Safety for Neopentyl Glycol Dimethacrylate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Neopentyl Glycol Dimethacrylate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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