Is NIACINAMIDE RIBOSIDE CHLORIDE safe in cosmetics?
NIACINAMIDE RIBOSIDE CHLORIDE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
GOOD
Cosmetic Ingredient
NIACINAMIDE RIBOSIDE CHLORIDE
NIACINAMIDE RIBOSIDE CHLORIDE (CAS 23111-00-4) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 23111-00-4 →
Function
Antioxidant, Skin Protecting
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide chloride
InChIKey
YABIFCKURFRPPO-IVOJBTPCSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — no specific prohibition; general cosmetic safety requirements apply
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Humectant
Editorial summary
Preliminary editorial summary for NIACINAMIDE RIBOSIDE CHLORIDE — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cosing-sourced
eu-permitted
antioxidant
needs-enrichment
Chemical Function
Antioxidant
Humectant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
26
SOURCE
EFSA / FDA GRAS
fda_gras_enriched
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Nicotinamide riboside chloride
FDA GRAS
FDA has no questions
GRN
635
Source of vitamin B3 in vitamin waters, protein shakes, nutrition bars, gum, chews, and powdered beverages at a maximum level of 0.0057% by weight as consumed.
View full food safety profile →Frequently Asked Questions
Is NIACINAMIDE RIBOSIDE CHLORIDE allowed in the EU?
NIACINAMIDE RIBOSIDE CHLORIDE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NIACINAMIDE RIBOSIDE CHLORIDE do in cosmetics?
NIACINAMIDE RIBOSIDE CHLORIDE functions as: Antioxidant, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 23111-00-4.
Is NIACINAMIDE RIBOSIDE CHLORIDE used outside cosmetics?
NIACINAMIDE RIBOSIDE CHLORIDE also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NIACINAMIDE RIBOSIDE CHLORIDE compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2-O-Ethyl Ascorbic Acid
EXCELLENT
Same category
Softener and conditioner
3-Glyceryl Ascorbate
EXCELLENT
Same category
Antioxidant, Humectant, Skin Conditio...
Allantoin Ascorbate
EXCELLENT
Same category
Antioxidant, Skin Conditioning, Skin ...
Aloe Vera Extract
EXCELLENT
Same category
Skin Conditioning, Antioxidant
Althaea Officinalis Callus Culture Extract
EXCELLENT
Same category
Antioxidant, skin protectant
Amaranthus Caudatus Seed Oil
EXCELLENT
Same category
Emollient, skin conditioning, antioxi...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
GOOD
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
GOOD
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
GOOD
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
GOOD
Similar safety
Humectant, Skin Conditioning - Humect...
(ASPERGILLUS/SACCHAROMYCES)/RICE FERMENT/BARLEY GRAIN MEAL/NELUMBO NUCIFERA FLOWER EXTRACT FERMENT EXTRACT FILTRATE
GOOD
Similar safety
Bleaching
(ASTRAGALUS MEMBRANACEUS/GLYCYRRHIZA URALENSIS (LICORICE)/PANAX GINSENG) ROOT/AMOMUM XANTHIOIDES SEED/HORDEUM VULGARE SPROUT/ARALIA CORDATA/ACHYRANTHES JAPONICA EXTRACT
GOOD
Similar safety
Skin Conditioning - Miscellaneous
Nicotinamide Riboside
GOOD
Chemical family
Skin conditioning (NAD+ precursor; ce...
NIACIN
GOOD
Browse nearby
Antistatic, Smoothing
NIACINAMIDE ASCORBATE
GOOD
Browse nearby
Skin Conditioning
Is NIACINAMIDE RIBOSIDE CHLORIDE in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for NIACINAMIDE RIBOSIDE CHLORIDE in your formulation.