Is NIACINAMIDE RIBOSIDE CHLORIDE safe in cosmetics?
NIACINAMIDE RIBOSIDE CHLORIDE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
Good
Cosmetic Ingredient
NIACINAMIDE RIBOSIDE CHLORIDE
NIACINAMIDE RIBOSIDE CHLORIDE (CAS 23111-00-4) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 23111-00-4 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin Protecting
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide chloride
InChIKey
YABIFCKURFRPPO-IVOJBTPCSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — no specific prohibition; general cosmetic safety requirements apply
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for NIACINAMIDE RIBOSIDE CHLORIDE.
Regulatory Flags
cosing-sourced
eu-permitted
antioxidant
needs-enrichment
Chemical Function
Antioxidant
Humectant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
26
Frequently Asked Questions
Is NIACINAMIDE RIBOSIDE CHLORIDE allowed in the EU?
NIACINAMIDE RIBOSIDE CHLORIDE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NIACINAMIDE RIBOSIDE CHLORIDE do in cosmetics?
NIACINAMIDE RIBOSIDE CHLORIDE functions as: Antioxidant, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 23111-00-4.
Is NIACINAMIDE RIBOSIDE CHLORIDE used outside cosmetics?
NIACINAMIDE RIBOSIDE CHLORIDE also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NIACINAMIDE RIBOSIDE CHLORIDE compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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