Is NICOTINALDEHYDE safe in cosmetics?
NICOTINALDEHYDE has a safety rating of "GOOD" in our database. EU status: permitted. US status: prohibited.
Good
Cosmetic Ingredient
NICOTINALDEHYDE
Also known as: 5-21-07-00334, BRN 0105343, EINECS 207-900-4, 3-Pyridenecarboxaldehyde, beta-Pyridinecarbonaldehyde (+1 more)
NICOTINALDEHYDE (CAS 500-22-1) is a cosmetic cosmetic ingredient functioning as Antimicrobial. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 500-22-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
NICOTINALDEHYDE is classified GHS Danger (H226, H302, H315, H317, H318, H334, H335, H341) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antimicrobial
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
pyridine-3-carbaldehyde
InChIKey
QJZUKDFHGGYHMC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Allowed. Not on the FDA prohibited/restricted list
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Expert Verdict
Expert safety assessment and concern-level summary for NICOTINALDEHYDE.
Regulatory Flags
cosing-sourced
eu-permitted
preservative
needs-enrichment
Known Synonyms
5-21-07-00334
BRN 0105343
EINECS 207-900-4
3-Pyridenecarboxaldehyde
beta-Pyridinecarbonaldehyde
UNII-840R4IDQ1T
Chemical Function
Biocide
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NICOTINALDEHYDE
ChEMBL ID
CHEMBL268493
Frequently Asked Questions
Is NICOTINALDEHYDE allowed in the EU?
NICOTINALDEHYDE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NICOTINALDEHYDE do in cosmetics?
NICOTINALDEHYDE functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 500-22-1.
Is NICOTINALDEHYDE used outside cosmetics?
NICOTINALDEHYDE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does NICOTINALDEHYDE have different safety status in cosmetics vs industrial chemicals?
NICOTINALDEHYDE is classified GHS Danger (H226, H302, H315, H317, H318, H334, H335, H341) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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