Regulatory Status
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Safety Data
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Expert Verdict
NDGA is a potent antioxidant permitted in EU cosmetics without concentration limits, though it lacks both SCCS and CIR safety opinions. Hepatotoxicity and nephrotoxicity documented in animal oral/IP studies, but topical application at 3% showed negligible systemic absorption.
Regulatory Flags
Frequently Asked Questions
Is Nordihydroguaiaretic Acid safe in cosmetics?
NDGA is a potent antioxidant permitted in EU cosmetics without concentration limits, though it lacks both SCCS and CIR safety opinions. Hepatotoxicity and nephrotoxicity documented in animal oral/IP studies, but topical application at 3% showed negligible systemic absorption. The EU classifies Nordihydroguaiaretic Acid as "permitted". Safety rating: MODERATE.
Is Nordihydroguaiaretic Acid allowed in the EU?
Nordihydroguaiaretic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Nordihydroguaiaretic Acid do in cosmetics?
Nordihydroguaiaretic Acid functions as: Antioxidant, Sebum Control, Photoprotective Agent. It is classified as a Antioxidant in our database. CAS number: 500-38-9.
What is the Margin of Safety for Nordihydroguaiaretic Acid?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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