O-TOLYL BIGUANIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
1 study endpoint found for O-TOLYL BIGUANIDE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | ca.50 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
O-TOLYL BIGUANIDE is listed in the EU CosIng database with functions: Antioxidant It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is O-TOLYL BIGUANIDE safe in cosmetics?
O-TOLYL BIGUANIDE is listed in the EU CosIng database with functions: Antioxidant It is permitted in the EU without specific restrictions. The EU classifies O-TOLYL BIGUANIDE as "Permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is O-TOLYL BIGUANIDE allowed in the EU?
O-TOLYL BIGUANIDE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does O-TOLYL BIGUANIDE do in cosmetics?
O-TOLYL BIGUANIDE functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 93-69-6.
What is the NOAEL for O-TOLYL BIGUANIDE?
The NOAEL (No Observed Adverse Effect Level) for O-TOLYL BIGUANIDE is ca.50 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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