Gamma-Oryzanol

INCI: ORYZANOL

CAS Number
11042-64-1
Function
Antioxidant; UV Absorber; Skin Conditioning; Antistat
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not a permitted OTC sunscreen active under 21 CFR 352; permitted as cosmetic antioxidant/skin conditioning; CIR assessed Oryza Sativa-derived ingredients safe (2006)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potent natural antioxidant with UV-absorbing capacity (UVB, approximately 315 nm); oil-soluble only with negligible systemic exposure from topical use due to poor dermal absorption; verify dermal LD50 data against primary sources before reliance.

โš ๏ธ
Concern Level: Low

Regulatory Flags

antioxidant uv-absorber plant-derived rice-bran oil-soluble no-sccs-opinion cir-assessed cannot-claim-spf-us

Frequently Asked Questions

Is Gamma-Oryzanol safe in cosmetics?

Potent natural antioxidant with UV-absorbing capacity (UVB, approximately 315 nm); oil-soluble only with negligible systemic exposure from topical use due to poor dermal absorption; verify dermal LD50 data against primary sources before reliance. The EU classifies Gamma-Oryzanol as "permitted". Safety rating: EXCELLENT.

Is Gamma-Oryzanol allowed in the EU?

Gamma-Oryzanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gamma-Oryzanol do in cosmetics?

Gamma-Oryzanol functions as: Antioxidant; UV Absorber; Skin Conditioning; Antistat. It is classified as a cosmetic ingredient in our database. CAS number: 11042-64-1.

What is the Margin of Safety for Gamma-Oryzanol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Gamma-Oryzanol in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Gamma-Oryzanol in your formulation.