Octoxynol-7

INCI: OCTOXYNOL-7

CAS Number
9002-93-1 (generic); 27177-02-2 (discrete)
Function
Surfactant — emulsifying, cleansing (trade name: Igepal CA-620)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR: safe in rinse-off; ≤ 5% in leave-on

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Residual EO and 1,4-dioxane present; irritation potential; no reported cosmetic use with safety relying on family read-across; environmental endocrine disruption degradation product; not eligible for COSMOS/ECOCERT certification.

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Concern Level: Moderate

Frequently Asked Questions

Is Octoxynol-7 safe in cosmetics?

Residual EO and 1,4-dioxane present; irritation potential; no reported cosmetic use with safety relying on family read-across; environmental endocrine disruption degradation product; not eligible for COSMOS/ECOCERT certification. The EU classifies Octoxynol-7 as "permitted". Safety rating: MODERATE.

Is Octoxynol-7 allowed in the EU?

Octoxynol-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Octoxynol-7 do in cosmetics?

Octoxynol-7 functions as: Surfactant — emulsifying, cleansing (trade name: Igepal CA-620). It is classified as a cosmetic ingredient in our database. CAS number: 9002-93-1 (generic); 27177-02-2 (discrete).

What is the Margin of Safety for Octoxynol-7?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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