Excellent Cosmetic Ingredient NOAEL Data

Agar

INCI: AGAR

CAS Number
9002-18-0
Function
Binder, Thickening Agent, Gelling Agent, Film Former
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS for food; widely permitted in cosmetics; no CIR restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Agar. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1140 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 30000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 15000 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 15000 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 25000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 6000 mg/kg bw/day oral rabbit Short Term Toxicity COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 650 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 1570 mg/kg bw/day oral mouse Developmental COSMOS_DB

Expert Verdict

Thermostable natural gelling agent from red algae with agarose-dominant structure providing firm gel textures and excellent safety profile, suitable for moisturizers, cleansers, deodorants, and preferred for COSMOS/ECOCERT formulations as a synthetic polymer alternative.

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Concern Level: None

Regulatory Flags

heavy_metal_testing_required marine_origin cosmos_ecocert_compatible ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Agar safe in cosmetics?

Thermostable natural gelling agent from red algae with agarose-dominant structure providing firm gel textures and excellent safety profile, suitable for moisturizers, cleansers, deodorants, and preferred for COSMOS/ECOCERT formulations as a synthetic polymer alternative. The EU classifies Agar as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Agar allowed in the EU?

Agar EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Agar do in cosmetics?

Agar functions as: Binder, Thickening Agent, Gelling Agent, Film Former. It is classified as a cosmetic ingredient in our database. CAS number: 9002-18-0.

What is the Margin of Safety for Agar?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Agar?

The NOAEL (No Observed Adverse Effect Level) for Agar is 1140 mg/kg bw/day based on a Developmental study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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