Is P-ISOPROPYLPHENYL METHYL KETONE safe in cosmetics?
P-ISOPROPYLPHENYL METHYL KETONE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
P-ISOPROPYLPHENYL METHYL KETONE
Also known as: Acetophenone, 4'-isopropyl-, Acetylcumene, p-, Cuminone, EINECS 211-433-1, FEMA No. 2927 (+7 more)
P-ISOPROPYLPHENYL METHYL KETONE (CAS 645-13-6) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 645-13-6 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
1-(4-propan-2-ylphenyl)ethanone
InChIKey
PDLCCNYKIIUWHA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (5)
JECFA Number
808
Source: WHO/JECFA
JECFA Evaluation
p-ISOPROPYLACETOPHENONE | 2023 | No safety concern at current levels of intake when used as a flavouring agent | Considered for specifications only | TRS 1050-JECFA 96/46 | FAS 48-JECFA 57/117
Source: WHO/JECFA
JECFA Evaluation
p-ISOPROPYLACETYLBENZENE | 2023 | No safety concern at current levels of intake when used as a flavouring agent | Considered for specifications only | TRS 1050-JECFA 96/46 | FAS 48-JECFA 57/117
Source: WHO/JECFA
JECFA Evaluation
p-ACETYLCUMENE | 2023 | No safety concern at current levels of intake when used as a flavouring agent | Considered for specifications only | TRS 1050-JECFA 96/46 | FAS 48-JECFA 57/117
Source: WHO/JECFA
JECFA Evaluation
METHYL p-ISOPROPYLPHENYL KETONE | 2023 | No safety concern at current levels of intake when used as a flavouring agent | Considered for specifications only | TRS 1050-JECFA 96/46 | FAS 48-JECFA 57/117
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for P-ISOPROPYLPHENYL METHYL KETONE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
Known Synonyms
Acetophenone, 4'-isopropyl-
Acetylcumene, p-
Cuminone
EINECS 211-433-1
FEMA No. 2927
p-Isopropylacetophenone
4'-Isopropylacetophenone
Isopropylacetylbenzene, p-
Methyl p-isopropylphenyl ketone
1-(4-(1-Methylethyl)phenyl)ethanone
NSC 9165
UNII-742ZKZ2A6D
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
pharmaceutical
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
P-ISOPROPYLACETOPHENONE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is P-ISOPROPYLPHENYL METHYL KETONE allowed in the EU?
P-ISOPROPYLPHENYL METHYL KETONE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does P-ISOPROPYLPHENYL METHYL KETONE do in cosmetics?
P-ISOPROPYLPHENYL METHYL KETONE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 645-13-6.
Is P-ISOPROPYLPHENYL METHYL KETONE used outside cosmetics?
P-ISOPROPYLPHENYL METHYL KETONE also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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MoS Calculator
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