Paeoniflorin

INCI: PAEONIFLORIN

CAS Number
23180-57-6
Function
Anti-inflammatory, Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” Listed in CTFA/PCPC dictionary; no FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited cosmetic-specific safety data; widely studied pharmacologically but few dedicated dermal safety studies; listed in Chinese Cosmetic Raw Materials Standards (CAFFCI 2010); GHS hazard statements H315/H319 apply to the pure compound

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Concern Level: Moderate

Frequently Asked Questions

Is Paeoniflorin safe in cosmetics?

Limited cosmetic-specific safety data; widely studied pharmacologically but few dedicated dermal safety studies; listed in Chinese Cosmetic Raw Materials Standards (CAFFCI 2010); GHS hazard statements H315/H319 apply to the pure compound The EU classifies Paeoniflorin as "permitted". Safety rating: GOOD.

Is Paeoniflorin allowed in the EU?

Paeoniflorin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Paeoniflorin do in cosmetics?

Paeoniflorin functions as: Anti-inflammatory, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 23180-57-6.

What is the Margin of Safety for Paeoniflorin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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