Palmitoyl Hexapeptide-14

INCI: PALMITOYL HEXAPEPTIDE-14

CAS Number
891498-01-4
Function
Skin Conditioning, Anti-aging, Firming, Smoothing
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” No FDA restriction; falls within CIR palmitoyl oligopeptide group

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bioactive at very low concentrations; stimulates collagen and extracellular matrix remodeling and inhibits matrix metalloproteinases; ensure formulation concentration stays within documented safe range (typically 1โ€“5 ppm active peptide).

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Concern Level: Low

Frequently Asked Questions

Is Palmitoyl Hexapeptide-14 safe in cosmetics?

Bioactive at very low concentrations; stimulates collagen and extracellular matrix remodeling and inhibits matrix metalloproteinases; ensure formulation concentration stays within documented safe range (typically 1โ€“5 ppm active peptide). The EU classifies Palmitoyl Hexapeptide-14 as "permitted". Safety rating: GOOD.

Is Palmitoyl Hexapeptide-14 allowed in the EU?

Palmitoyl Hexapeptide-14 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Palmitoyl Hexapeptide-14 do in cosmetics?

Palmitoyl Hexapeptide-14 functions as: Skin Conditioning, Anti-aging, Firming, Smoothing. It is classified as a cosmetic ingredient in our database. CAS number: 891498-01-4.

What is the Margin of Safety for Palmitoyl Hexapeptide-14?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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