Good Cosmetic Ingredient NOAEL Data GHS Classified

PEG-160M

CAS Number
25322-68-3
Function
Binding, Emulsion Stabilising, Viscosity Controlling
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status Permitted
🇺🇸 US Status permitted
US Notes CIR: S - JACT 1(4):35-54, 1982

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

10 study endpoints found for PEG-160M. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1690 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 2000 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 1820 mg/kg bw/day oral dog Chronic COSMOS_DB
NOAEL 1600 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 4050 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 230 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10900 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1128 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 25000 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Expert Verdict

PEG-160M is listed in the EU CosIng database with functions: Binding, Emulsion Stabilising, Viscosity Controlling It is permitted in the EU without specific restrictions.

⚠️
Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is PEG-160M safe in cosmetics?

PEG-160M is listed in the EU CosIng database with functions: Binding, Emulsion Stabilising, Viscosity Controlling It is permitted in the EU without specific restrictions. The EU classifies PEG-160M as "Permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is PEG-160M allowed in the EU?

PEG-160M EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG-160M do in cosmetics?

PEG-160M functions as: Binding, Emulsion Stabilising, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 25322-68-3.

What is the NOAEL for PEG-160M?

The NOAEL (No Observed Adverse Effect Level) for PEG-160M is 1690 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

Compliance Tools

Check PEG-160M compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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