Good Cosmetic Ingredient NOAEL Data

PEG-40 SORBITAN LAURATE

CAS Number
9005-64-5
Function
Surfactant - Cleansing, Surfactant - Emulsifying
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes CIR: SQ - Final Report 6/2015 Available from CIR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

9 study endpoints found for PEG-40 SORBITAN LAURATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 25000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 3000 mg/kg bw/day oral hamster Chronic COSMOS_DB
NOAEL 25000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 6000 mg/kg bw/day oral hamster Short Term Toxicity COSMOS_DB
NOAEL >=1000 mg/kg bw/day oral rat oral REACH
NOAEL >=2 other oral rat oral REACH
NOAEL >=2 other oral rat oral REACH
NOAEL >=2 other oral rat oral REACH
NOAEL >=2 other oral rat oral REACH

Expert Verdict

PEG-40 SORBITAN LAURATE is listed in the EU CosIng database with functions: Surfactant - Cleansing, Surfactant - Emulsifying It is permitted in the EU without specific restrictions.

โš ๏ธ
Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted surfactant needs-enrichment eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is PEG-40 SORBITAN LAURATE safe in cosmetics?

PEG-40 SORBITAN LAURATE is listed in the EU CosIng database with functions: Surfactant - Cleansing, Surfactant - Emulsifying It is permitted in the EU without specific restrictions. The EU classifies PEG-40 SORBITAN LAURATE as "Permitted". Safety rating: GOOD. 9 toxicological study endpoint(s) are available in our database.

Is PEG-40 SORBITAN LAURATE allowed in the EU?

PEG-40 SORBITAN LAURATE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG-40 SORBITAN LAURATE do in cosmetics?

PEG-40 SORBITAN LAURATE functions as: Surfactant - Cleansing, Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9005-64-5.

What is the NOAEL for PEG-40 SORBITAN LAURATE?

The NOAEL (No Observed Adverse Effect Level) for PEG-40 SORBITAN LAURATE is 25000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 9 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is PEG-40 SORBITAN LAURATE in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for PEG-40 SORBITAN LAURATE in your formulation.