Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Alginate (Sodium Alginate). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 7500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | guinea pig | Chronic | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | cat | Subchronic | COSMOS_DB |
| NOAEL | 11250 mg/kg bw/day | oral | dog | Chronic | COSMOS_DB |
| NOAEL | 37500 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| dose_tested | 7500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| dose_tested | 5000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 2000 mg/kg bw/day | oral | guinea pig | Chronic | COSMOS_DB |
| dose_tested | 2500 mg/kg bw/day | oral | cat | Subchronic | COSMOS_DB |
Expert Verdict
Sodium alginate has a good safety profile and is generally considered safe for cosmetic use with negligible skin absorption.
Regulatory Flags
Frequently Asked Questions
Is Alginate (Sodium Alginate) safe in cosmetics?
Sodium alginate has a good safety profile and is generally considered safe for cosmetic use with negligible skin absorption. The EU classifies Alginate (Sodium Alginate) as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Alginate (Sodium Alginate) allowed in the EU?
Alginate (Sodium Alginate) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Alginate (Sodium Alginate) do in cosmetics?
Alginate (Sodium Alginate) functions as: Thickener. It is classified as a Cosmetic Ingredient in our database. CAS number: 9005-38-3.
What is the Margin of Safety for Alginate (Sodium Alginate)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Alginate (Sodium Alginate)?
The NOAEL (No Observed Adverse Effect Level) for Alginate (Sodium Alginate) is 7500 mg/kg bw/day based on a Chronic study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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