Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for PEG-6 Dioleate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3000 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| dose_tested | 3000 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
Expert Verdict
PEG-6 is below the penetration enhancement threshold of PEG-12 and longer chain dioleates; contains trace 1,4-dioxane as impurity; peroxide formation possible on storage.
Regulatory Flags
Frequently Asked Questions
Is PEG-6 Dioleate safe in cosmetics?
PEG-6 is below the penetration enhancement threshold of PEG-12 and longer chain dioleates; contains trace 1,4-dioxane as impurity; peroxide formation possible on storage. The EU classifies PEG-6 Dioleate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is PEG-6 Dioleate allowed in the EU?
PEG-6 Dioleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-6 Dioleate do in cosmetics?
PEG-6 Dioleate functions as: Surfactant - emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 9005-07-6.
What is the Margin of Safety for PEG-6 Dioleate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for PEG-6 Dioleate?
The NOAEL (No Observed Adverse Effect Level) for PEG-6 Dioleate is 3000 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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