PEG-9
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for PEG-9. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1690 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 1820 mg/kg bw/day | oral | dog | Chronic | COSMOS_DB |
| NOAEL | 1600 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 4050 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 230 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 7500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 10900 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1128 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 25000 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
1,4-Dioxane and ethylene oxide residuals require monitoring — lower MW PEGs may carry higher impurity levels; avoid use on significantly damaged or compromised skin
Regulatory Flags
Frequently Asked Questions
Is PEG-9 safe in cosmetics?
1,4-Dioxane and ethylene oxide residuals require monitoring — lower MW PEGs may carry higher impurity levels; avoid use on significantly damaged or compromised skin The EU classifies PEG-9 as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is PEG-9 allowed in the EU?
PEG-9 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-9 do in cosmetics?
PEG-9 functions as: Humectant, solvent, skin-conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 25322-68-3.
What is the Margin of Safety for PEG-9?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for PEG-9?
The NOAEL (No Observed Adverse Effect Level) for PEG-9 is 1690 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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