Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Phenethyl 2-Ethylbutyrate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3.28 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 3.28 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Limited direct toxicological data; safety supported by read-across to phenethyl alcohol and structurally related esters
Regulatory Flags
Frequently Asked Questions
Is Phenethyl 2-Ethylbutyrate safe in cosmetics?
Limited direct toxicological data; safety supported by read-across to phenethyl alcohol and structurally related esters The EU classifies Phenethyl 2-Ethylbutyrate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Phenethyl 2-Ethylbutyrate allowed in the EU?
Phenethyl 2-Ethylbutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenethyl 2-Ethylbutyrate do in cosmetics?
Phenethyl 2-Ethylbutyrate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 68922-11-2.
What is the Margin of Safety for Phenethyl 2-Ethylbutyrate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Phenethyl 2-Ethylbutyrate?
The NOAEL (No Observed Adverse Effect Level) for Phenethyl 2-Ethylbutyrate is 3.28 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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