Phenolsulfonphthalein

INCI: PHENOLSULFONPHTHALEIN

CAS Number
143-74-8
Function
pH indicator, colorant (non-cosmetic primary use)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not FDA-approved as a color additive for cosmetics under 21 CFR Parts 73/74. Primarily a diagnostic/laboratory reagent.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Phenolsulfonphthalein is not approved as a cosmetic colorant in either EU or US, with hazard classifications including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).

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Concern Level: Moderate

Regulatory Flags

colorant

Frequently Asked Questions

Is Phenolsulfonphthalein safe in cosmetics?

Phenolsulfonphthalein is not approved as a cosmetic colorant in either EU or US, with hazard classifications including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). The EU classifies Phenolsulfonphthalein as "permitted". Safety rating: MODERATE.

Is Phenolsulfonphthalein allowed in the EU?

Phenolsulfonphthalein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phenolsulfonphthalein do in cosmetics?

Phenolsulfonphthalein functions as: pH indicator, colorant (non-cosmetic primary use). It is classified as a cosmetic ingredient in our database. CAS number: 143-74-8.

What is the Margin of Safety for Phenolsulfonphthalein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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