Is Phenoxyethyl Methacrylate safe in cosmetics?
Phenoxyethyl Methacrylate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Phenoxyethyl Methacrylate
Also known as: 2-Phenoxyethyl 2-methylprop-2-enoate, 2-Propenoic acid, 2-methyl-, 2-phenoxyethyl ester, EINECS 234-201-1, Methacrylic acid, 2-phenoxyethyl ester, 2-Phenoxyethyl methacrylate
INCI: PHENOXYETHYL METHACRYLATE
Phenoxyethyl Methacrylate (CAS 10595-06-9) is a cosmetic cosmetic ingredient functioning as Film former / monomer for cosmetic polymers (primarily nail products). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 10595-06-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Phenoxyethyl Methacrylate is classified GHS CMR hazard (H315, H317, H319, H335, H361d, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film former / monomer for cosmetic polymers (primarily nail products)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-phenoxyethyl 2-methylprop-2-enoate
InChIKey
CEXQWAAGPPNOQF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: safe when formulated to avoid irritation; methacrylate monomers require directions to avoid skin contact
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phenoxyethyl Methacrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Binder
Expert Verdict
Expert safety assessment and concern-level summary for Phenoxyethyl Methacrylate.
Regulatory Flags
potential-allergen
Known Synonyms
2-Phenoxyethyl 2-methylprop-2-enoate
2-Propenoic acid, 2-methyl-, 2-phenoxyethyl ester
EINECS 234-201-1
Methacrylic acid, 2-phenoxyethyl ester
2-Phenoxyethyl methacrylate
Chemical Function
Binder
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185186
Frequently Asked Questions
Is Phenoxyethyl Methacrylate allowed in the EU?
Phenoxyethyl Methacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenoxyethyl Methacrylate do in cosmetics?
Phenoxyethyl Methacrylate functions as: Film former / monomer for cosmetic polymers (primarily nail products). It is classified as a cosmetic ingredient in our database. CAS number: 10595-06-9.
Is Phenoxyethyl Methacrylate used outside cosmetics?
Phenoxyethyl Methacrylate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Phenoxyethyl Methacrylate have different safety status in cosmetics vs industrial chemicals?
Phenoxyethyl Methacrylate is classified GHS CMR hazard (H315, H317, H319, H335, H361d, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Phenoxyethyl Methacrylate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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