Phenyldimethoxyacetophenone

INCI: PHENYLDIMETHOXYACETOPHENONE

CAS Number
24650-42-8 [^1_8]
Function
Photoinitiator used in UV-curable nail gel systems; not a traditional cosmetic active
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA โ€” no specific ban; used in UV nail products. No CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generates free radicals under UV; skin exposure during application can cause sensitization. Ensure negligible migration to surrounding skin.

โš ๏ธ
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Phenyldimethoxyacetophenone safe in cosmetics?

Generates free radicals under UV; skin exposure during application can cause sensitization. Ensure negligible migration to surrounding skin. The EU classifies Phenyldimethoxyacetophenone as "permitted". Safety rating: MODERATE.

Is Phenyldimethoxyacetophenone allowed in the EU?

Phenyldimethoxyacetophenone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phenyldimethoxyacetophenone do in cosmetics?

Phenyldimethoxyacetophenone functions as: Photoinitiator used in UV-curable nail gel systems; not a traditional cosmetic active. It is classified as a cosmetic ingredient in our database. CAS number: 24650-42-8 [^1_8].

What is the Margin of Safety for Phenyldimethoxyacetophenone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Phenyldimethoxyacetophenone in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Phenyldimethoxyacetophenone in your formulation.