Regulatory Status
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Safety Data
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Expert Verdict
Data gap: insufficient published toxicological data. If used as colorant, regulatory compliance requires Annex IV listing (EU) or FDA color additive approval (US). Confirm intended function with supplier.
Regulatory Flags
Frequently Asked Questions
Is Phenylethylidene-Bis-Indole safe in cosmetics?
Data gap: insufficient published toxicological data. If used as colorant, regulatory compliance requires Annex IV listing (EU) or FDA color additive approval (US). Confirm intended function with supplier. The EU classifies Phenylethylidene-Bis-Indole as "permitted". Safety rating: MODERATE.
Is Phenylethylidene-Bis-Indole allowed in the EU?
Phenylethylidene-Bis-Indole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenylethylidene-Bis-Indole do in cosmetics?
Phenylethylidene-Bis-Indole functions as: Skin conditioning / colorant (indole-derivative; imparts color). It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (CosIng-listed) [^1_17].
What is the Margin of Safety for Phenylethylidene-Bis-Indole?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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