Phytosphingosine Glycolate

INCI: PHYTOSPHINGOSINE GLYCOLATE

CAS Number
Not publicly assigned (salt of CAS 554-62-1 + glycolic acid CAS 79-14-1)
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA permitted for cosmetic use; not specifically restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Glycolate moiety is an AHA; formulation pH critically affects irritation potential—keep pH ≥3.5 for leave-on products; may increase photosensitivity, sunscreen recommended in finished product.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Phytosphingosine Glycolate safe in cosmetics?

Glycolate moiety is an AHA; formulation pH critically affects irritation potential—keep pH ≥3.5 for leave-on products; may increase photosensitivity, sunscreen recommended in finished product. The EU classifies Phytosphingosine Glycolate as "permitted". Safety rating: GOOD.

Is Phytosphingosine Glycolate allowed in the EU?

Phytosphingosine Glycolate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phytosphingosine Glycolate do in cosmetics?

Phytosphingosine Glycolate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (salt of CAS 554-62-1 + glycolic acid CAS 79-14-1).

What is the Margin of Safety for Phytosphingosine Glycolate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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