Phytosphingosine PCA

INCI: PHYTOSPHINGOSINE PCA

CAS Number
291520-27-9
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted for cosmetic use; not specifically restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PCA is a natural NMF component with excellent biocompatibility; enhanced stability versus free base phytosphingosine; typical use 0.1โ€“0.5%

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Concern Level: Low

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Phytosphingosine PCA safe in cosmetics?

PCA is a natural NMF component with excellent biocompatibility; enhanced stability versus free base phytosphingosine; typical use 0.1โ€“0.5% The EU classifies Phytosphingosine PCA as "permitted". Safety rating: GOOD.

Is Phytosphingosine PCA allowed in the EU?

Phytosphingosine PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phytosphingosine PCA do in cosmetics?

Phytosphingosine PCA functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 291520-27-9.

What is the Margin of Safety for Phytosphingosine PCA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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