Moderate Cosmetic Ingredient

Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters

INCI: PLUKENETIA VOLUBILIS SEED OIL/OLEIC ACID AMINOPROPANEDIOL AMIDES/ESTERS

CAS Number
Not assigned (chemically modified derivative)
Function
Emollient, skin conditioning, surfactant (amide/ester derivative enhances emulsification)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA restriction; requires safety substantiation under MoCRA as modified ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Chemical modification creates a new toxicological entity. Parent oil safety cannot fully read-across. Amide/ester linkages require hydrolysis stability data, ocular irritation testing, and full dermal sensitization testing. Impurity profile (residual aminopropanediol) must be controlled.

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Concern Level: High

Regulatory Flags

plant-oil potential-allergen

Frequently Asked Questions

Is Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters safe in cosmetics?

Chemical modification creates a new toxicological entity. Parent oil safety cannot fully read-across. Amide/ester linkages require hydrolysis stability data, ocular irritation testing, and full dermal sensitization testing. Impurity profile (residual aminopropanediol) must be controlled. The EU classifies Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters as "permitted". Safety rating: MODERATE.

Is Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters allowed in the EU?

Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters do in cosmetics?

Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters functions as: Emollient, skin conditioning, surfactant (amide/ester derivative enhances emulsification). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (chemically modified derivative).

What is the Margin of Safety for Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Plukenetia Volubilis Seed Oil/Oleic Acid Aminopropanediol Amides/Esters compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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