Is PNA safe in cosmetics?
PNA has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
POOR
Cosmetic Ingredient
PNA
PNA (CAS Ambiguous — if p-Nitroaniline (4-Nitroaniline): 100-01-6) is a cosmetic cosmetic ingredient functioning as Hair dye intermediate (historically). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
CAS Number
Ambiguous — if p-Nitroaniline (4-Nitroaniline): 100-01-6
View industrial chemical safety profile →
Function
Hair dye intermediate (historically)
Editorial assessment
POOR
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not approved as a color additive by FDA; not GRAS for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PNA.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for PNA — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is PNA allowed in the EU?
PNA EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does PNA do in cosmetics?
PNA functions as: Hair dye intermediate (historically). It is classified as a cosmetic ingredient in our database. CAS number: Ambiguous — if p-Nitroaniline (4-Nitroaniline): 100-01-6.
Compliance Tools
Check PNA compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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