Good Cosmetic Ingredient NOAEL Data

Pogostemon Cablin Leaf Oil

INCI: POGOSTEMON CABLIN LEAF OIL

CAS Number
8014-09-3
Function
Fragrance, skin conditioning, masking
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. 0.001%
🇺🇸 US Status permitted
US Notes FDA permitted; EAFUS listed; FEMA approved for flavor use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Pogostemon Cablin Leaf Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 12 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Not phototoxic. Main constituents: patchouli alcohol, α-bulnesene, α-guaiene, caryophyllene. Must comply with IFRA 51st Amendment category limits.

⚠️
Concern Level: Low

Regulatory Flags

plant-oil fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Pogostemon Cablin Leaf Oil safe in cosmetics?

Not phototoxic. Main constituents: patchouli alcohol, α-bulnesene, α-guaiene, caryophyllene. Must comply with IFRA 51st Amendment category limits. The EU classifies Pogostemon Cablin Leaf Oil as "restricted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Pogostemon Cablin Leaf Oil allowed in the EU?

Pogostemon Cablin Leaf Oil EU regulatory status: restricted. Maximum allowed concentration: 0.001%. This is based on EU Regulation 1223/2009 and its amendments.

What does Pogostemon Cablin Leaf Oil do in cosmetics?

Pogostemon Cablin Leaf Oil functions as: Fragrance, skin conditioning, masking. It is classified as a cosmetic ingredient in our database. CAS number: 8014-09-3.

What is the Margin of Safety for Pogostemon Cablin Leaf Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Pogostemon Cablin Leaf Oil?

The NOAEL (No Observed Adverse Effect Level) for Pogostemon Cablin Leaf Oil is 12 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

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