Poloxamine 1102

INCI: POLOXAMINE 1102

CAS Number
11111-34-5
Function
Surfactant – Cleansing; Surfactant – Emulsifying; Fragrance Functional
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA monograph; no CIR safety assessment

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Poloxamine 1102 presents ethoxylation impurity concerns including 1,4-dioxane, EO, and PO with approximately 20% EO content; supplier SDS and read-across data required for CPSR due to lack of dedicated safety monograph.

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is Poloxamine 1102 safe in cosmetics?

Poloxamine 1102 presents ethoxylation impurity concerns including 1,4-dioxane, EO, and PO with approximately 20% EO content; supplier SDS and read-across data required for CPSR due to lack of dedicated safety monograph. The EU classifies Poloxamine 1102 as "permitted". Safety rating: MODERATE.

Is Poloxamine 1102 allowed in the EU?

Poloxamine 1102 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamine 1102 do in cosmetics?

Poloxamine 1102 functions as: Surfactant – Cleansing; Surfactant – Emulsifying; Fragrance Functional. It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.

What is the Margin of Safety for Poloxamine 1102?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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