Poloxamine 1504

INCI: POLOXAMINE 1504

CAS Number
11111-34-5
Function
Surfactant – emulsifying, surfactant – cleansing, solubilizer
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted by FDA; permitted under manufacturer GRAS-equivalent responsibility

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential 1,4-dioxane, ethylene oxide, propylene oxide impurities — require purification control

⚠️
Concern Level: Moderate

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Poloxamine 1504 safe in cosmetics?

Potential 1,4-dioxane, ethylene oxide, propylene oxide impurities — require purification control The EU classifies Poloxamine 1504 as "permitted". Safety rating: GOOD.

Is Poloxamine 1504 allowed in the EU?

Poloxamine 1504 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamine 1504 do in cosmetics?

Poloxamine 1504 functions as: Surfactant – emulsifying, surfactant – cleansing, solubilizer. It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.

What is the Margin of Safety for Poloxamine 1504?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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