Poloxamine 904

INCI: POLOXAMINE 904

CAS Number
11111-34-5
Function
Surfactant – Emulsifying; Fragrance functional
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No direct CIR review; CIR reviewed structurally related poloxamers safe as used with impurity controls

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Residual 1,4-dioxane, ethylene oxide, and propylene oxide impurities must be controlled below established limits.

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is Poloxamine 904 safe in cosmetics?

Residual 1,4-dioxane, ethylene oxide, and propylene oxide impurities must be controlled below established limits. The EU classifies Poloxamine 904 as "permitted". Safety rating: GOOD.

Is Poloxamine 904 allowed in the EU?

Poloxamine 904 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamine 904 do in cosmetics?

Poloxamine 904 functions as: Surfactant – Emulsifying; Fragrance functional. It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.

What is the Margin of Safety for Poloxamine 904?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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