Good Cosmetic Ingredient

Poly(1,4-Butanediol)-14

INCI: POLY(1,4-BUTANEDIOL)-14

CAS Number
25190-06-1 (parent PTMEG; variant-specific CAS not individually assigned in public databases)
Function
Skin conditioning, emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically regulated by FDA; not on CIR priority list; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Polymer backbone has good safety profile with negligible absorption. Primary concern is residual 1,4-butanediol monomer; CIR found insufficient data for monomer safety, so monomer content must be verified to remain below specification limits.

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Concern Level: Moderate

Frequently Asked Questions

Is Poly(1,4-Butanediol)-14 safe in cosmetics?

Polymer backbone has good safety profile with negligible absorption. Primary concern is residual 1,4-butanediol monomer; CIR found insufficient data for monomer safety, so monomer content must be verified to remain below specification limits. The EU classifies Poly(1,4-Butanediol)-14 as "permitted". Safety rating: GOOD.

Is Poly(1,4-Butanediol)-14 allowed in the EU?

Poly(1,4-Butanediol)-14 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poly(1,4-Butanediol)-14 do in cosmetics?

Poly(1,4-Butanediol)-14 functions as: Skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 25190-06-1 (parent PTMEG; variant-specific CAS not individually assigned in public databases).

What is the Margin of Safety for Poly(1,4-Butanediol)-14?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Poly(1,4-Butanediol)-14 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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