Polybutylene Glycol-10

INCI: POLYBUTYLENE GLYCOL-10

CAS Number
Not publicly assigned (polyethers of 1,3-butanediol, ~10 repeat units)
Function
Skin conditioning, humectant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes PCPC listed; no FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

1,4-Dioxane contamination potential as with all polyether/glycol polymers โ€” require supplier specification <10 ppm. Ethylene oxide residues not expected (butylene-based), but verify manufacturing process.

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Concern Level: Moderate

Frequently Asked Questions

Is Polybutylene Glycol-10 safe in cosmetics?

1,4-Dioxane contamination potential as with all polyether/glycol polymers โ€” require supplier specification <10 ppm. Ethylene oxide residues not expected (butylene-based), but verify manufacturing process. The EU classifies Polybutylene Glycol-10 as "permitted". Safety rating: MODERATE.

Is Polybutylene Glycol-10 allowed in the EU?

Polybutylene Glycol-10 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polybutylene Glycol-10 do in cosmetics?

Polybutylene Glycol-10 functions as: Skin conditioning, humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (polyethers of 1,3-butanediol, ~10 repeat units).

What is the Margin of Safety for Polybutylene Glycol-10?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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