Polycaprolactoyl Cyclodextrin

INCI: POLYCAPROLACTOYL CYCLODEXTRIN

CAS Number
Not established in major registries
Function
Encapsulation and delivery system (cyclodextrin-polycaprolactone conjugate)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR review; no specific FDA restriction. Falls under general cosmetic ingredient safety responsibility of manufacturer.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Significant data gap. A CPSR assessor would require supplier safety dossier with molecular weight distribution, residual monomer levels, dermal irritation, and sensitization data before sign-off.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Polycaprolactoyl Cyclodextrin safe in cosmetics?

Significant data gap. A CPSR assessor would require supplier safety dossier with molecular weight distribution, residual monomer levels, dermal irritation, and sensitization data before sign-off. The EU classifies Polycaprolactoyl Cyclodextrin as "permitted". Safety rating: MODERATE.

Is Polycaprolactoyl Cyclodextrin allowed in the EU?

Polycaprolactoyl Cyclodextrin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polycaprolactoyl Cyclodextrin do in cosmetics?

Polycaprolactoyl Cyclodextrin functions as: Encapsulation and delivery system (cyclodextrin-polycaprolactone conjugate). It is classified as a cosmetic ingredient in our database. CAS number: Not established in major registries.

What is the Margin of Safety for Polycaprolactoyl Cyclodextrin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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