Polygonum Multiflorum Extract

INCI: POLYGONUM MULTIFLORUM EXTRACT

CAS Number
2972-94-3
Function
Antioxidant, Hair conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; permitted under general cosmetic regulations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains anthraquinones including emodin, a known phototoxicant with documented genotoxicity flags in vitro; established hepatotoxicity via oral route raises safety scrutiny; reported allergic reactions in topical use.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Polygonum Multiflorum Extract safe in cosmetics?

Contains anthraquinones including emodin, a known phototoxicant with documented genotoxicity flags in vitro; established hepatotoxicity via oral route raises safety scrutiny; reported allergic reactions in topical use. The EU classifies Polygonum Multiflorum Extract as "permitted". Safety rating: MODERATE.

Is Polygonum Multiflorum Extract allowed in the EU?

Polygonum Multiflorum Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polygonum Multiflorum Extract do in cosmetics?

Polygonum Multiflorum Extract functions as: Antioxidant, Hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 2972-94-3.

What is the Margin of Safety for Polygonum Multiflorum Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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