Polyquaternium-37

INCI: POLYQUATERNIUM-37

CAS Number
26161-33-1
Function
Thickener; conditioning agent; rheology modifier
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted or prohibited under 21 CFR. Reported in FDA VCRP. Listed on TSCA inventory confirming US commercial status. Subject to MoCRA facility registration and product listing. CIR Expert Panel concluded safe in present use practices.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Polyquaternium-37 (CAS 26161-33-1) is permitted in the EU under Regulation (EC) No 1223/2009 with no concentration restrictions, and permitted in the US with no restrictions under 21 CFR; CIR (2012) concluded safe in present practices of use.

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Concern Level: None

Regulatory Flags

polymer cationic film-forming rheology-modifier conditioning antistatic cold-processable no-concentration-cap

Frequently Asked Questions

Is Polyquaternium-37 safe in cosmetics?

Polyquaternium-37 (CAS 26161-33-1) is permitted in the EU under Regulation (EC) No 1223/2009 with no concentration restrictions, and permitted in the US with no restrictions under 21 CFR; CIR (2012) concluded safe in present practices of use. The EU classifies Polyquaternium-37 as "permitted". Safety rating: EXCELLENT.

Is Polyquaternium-37 allowed in the EU?

Polyquaternium-37 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyquaternium-37 do in cosmetics?

Polyquaternium-37 functions as: Thickener; conditioning agent; rheology modifier. It is classified as a cosmetic ingredient in our database. CAS number: 26161-33-1.

What is the Margin of Safety for Polyquaternium-37?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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