Excellent Cosmetic Ingredient NOAEL Data

Ceratonia Siliqua Gum

INCI: CERATONIA SILIQUA GUM

CAS Number
9000-40-2
Function
rheology modifier, thickener, gelling agent, stabilizer
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes GRAS for food; widely used in cosmetics. No restriction.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Ceratonia Siliqua Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1300 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 1000 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 1300 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 910 mg/kg bw/day oral rabbit Developmental COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Subchronic COSMOS_DB
NOAEL 2500 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB

Expert Verdict

Natural galactomannan from carob seeds prized for its unique synergistic interaction with xanthan gum — together they form elastic gels at concentrations where neither gels alone, enabling novel texture design. Cold-insoluble: requires full hydration at ≥80 °C. Use level 0.5–1.5%. Fully biodegradable, exempt from EU REACH SPM restriction, COSMOS/ECOCERT compliant. The primary choice when elastic gel textures are desired in naturally-derived formulations.

⚠️
Concern Level: None

Regulatory Flags

eu-compliant biodegradable reach-spm-exempt natural-polymer cosmos-eligible ecocert gras xanthan-synergy elastic-gel hot-process-required carbomer-alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Ceratonia Siliqua Gum safe in cosmetics?

Natural galactomannan from carob seeds prized for its unique synergistic interaction with xanthan gum — together they form elastic gels at concentrations where neither gels alone, enabling novel texture design. Cold-insoluble: requires full hydration at ≥80 °C. Use level 0.5–1.5%. Fully biodegradable, exempt from EU REACH SPM restriction, COSMOS/ECOCERT compliant. The primary choice when elastic gel textures are desired in naturally-derived formulations. The EU classifies Ceratonia Siliqua Gum as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Ceratonia Siliqua Gum allowed in the EU?

Ceratonia Siliqua Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ceratonia Siliqua Gum do in cosmetics?

Ceratonia Siliqua Gum functions as: rheology modifier, thickener, gelling agent, stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 9000-40-2.

What is the Margin of Safety for Ceratonia Siliqua Gum?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ceratonia Siliqua Gum?

The NOAEL (No Observed Adverse Effect Level) for Ceratonia Siliqua Gum is 1000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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