Porphobilinogen Lactam

INCI: NOT LISTED

CAS Number
No CAS number identified in CosIng or major cosmetic databases
Function
Biochemical intermediate in heme biosynthesis; cosmetic function not established
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not recognized as a cosmetic ingredient; no GRAS or monograph status

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Biochemical intermediate not established as a cosmetic raw material; complete toxicological dossier required including genotoxicity, repeated-dose toxicity, and dermal absorption studies before formulation use.

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Concern Level: High

Frequently Asked Questions

Is Porphobilinogen Lactam safe in cosmetics?

Biochemical intermediate not established as a cosmetic raw material; complete toxicological dossier required including genotoxicity, repeated-dose toxicity, and dermal absorption studies before formulation use. The EU classifies Porphobilinogen Lactam as "permitted". Safety rating: MODERATE.

Is Porphobilinogen Lactam allowed in the EU?

Porphobilinogen Lactam EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Porphobilinogen Lactam do in cosmetics?

Porphobilinogen Lactam functions as: Biochemical intermediate in heme biosynthesis; cosmetic function not established. It is classified as a cosmetic ingredient in our database. CAS number: No CAS number identified in CosIng or major cosmetic databases.

What is the Margin of Safety for Porphobilinogen Lactam?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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