Moderate Cosmetic Ingredient

PPG-12/SMDI Copolymer

INCI: PPG-12/SMDI COPOLYMER

CAS Number
Not readily available (polyurethane copolymer)
Function
Film former (SMDI = bis(4-isocyanatocyclohexyl)methane / H₁₂MDI-based polyurethane segment)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific restriction; limited publicly available CIR data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Residual isocyanate monomer (SMDI / H₁₂MDI, CAS 5124-30-1) requires confirmation of complete reaction and residual monomer levels below detection. Inhalation concern if used in spray products. Limited published safety data compared to other PPG derivatives.

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Concern Level: Moderate

Frequently Asked Questions

Is PPG-12/SMDI Copolymer safe in cosmetics?

Residual isocyanate monomer (SMDI / H₁₂MDI, CAS 5124-30-1) requires confirmation of complete reaction and residual monomer levels below detection. Inhalation concern if used in spray products. Limited published safety data compared to other PPG derivatives. The EU classifies PPG-12/SMDI Copolymer as "permitted". Safety rating: MODERATE.

Is PPG-12/SMDI Copolymer allowed in the EU?

PPG-12/SMDI Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PPG-12/SMDI Copolymer do in cosmetics?

PPG-12/SMDI Copolymer functions as: Film former (SMDI = bis(4-isocyanatocyclohexyl)methane / H₁₂MDI-based polyurethane segment). It is classified as a cosmetic ingredient in our database. CAS number: Not readily available (polyurethane copolymer).

What is the Margin of Safety for PPG-12/SMDI Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check PPG-12/SMDI Copolymer compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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