Regulatory Status
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Safety Data
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Expert Verdict
Pregnane is a steroid skeleton, not intended for direct cosmetic use. Any derivative with hormonal or endocrine activity would be prohibited under EU Annex II. Do not formulate with this unless referencing a specific pregnane derivative with its own safety dossier.
Frequently Asked Questions
Is Pregnane safe in cosmetics?
Pregnane is a steroid skeleton, not intended for direct cosmetic use. Any derivative with hormonal or endocrine activity would be prohibited under EU Annex II. Do not formulate with this unless referencing a specific pregnane derivative with its own safety dossier. The EU classifies Pregnane as "prohibited". Safety rating: MODERATE.
Is Pregnane allowed in the EU?
Pregnane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Pregnane do in cosmetics?
Pregnane functions as: Not a standard cosmetic functional ingredient — it is the parent C₂₁ steroid backbone for pregnane-derived compounds. It is classified as a cosmetic ingredient in our database. CAS number: 481-26-5.
What is the Margin of Safety for Pregnane?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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