Propyl Butyrate

INCI: PROPYL BUTYRATE

CAS Number
105-66-8
Function
Fragrance ingredient, Solvent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; FEMA GRAS (No. 2934) as flavoring agent; CIR assessed safe as part of alkyl esters group

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Flammable (flash point ~39°C); classified as mild irritant to skin/eyes (H315, H319, H335) at undiluted concentrations

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Propyl Butyrate safe in cosmetics?

Flammable (flash point ~39°C); classified as mild irritant to skin/eyes (H315, H319, H335) at undiluted concentrations The EU classifies Propyl Butyrate as "permitted". Safety rating: GOOD.

Is Propyl Butyrate allowed in the EU?

Propyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propyl Butyrate do in cosmetics?

Propyl Butyrate functions as: Fragrance ingredient, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 105-66-8.

What is the Margin of Safety for Propyl Butyrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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