Pyridoxal

INCI: PYRIDOXAL

CAS Number
66-72-8
Function
Skin conditioning agent, antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no FDA restrictions. Vitamin B6 aldehyde form; CIR has not conducted a dedicated review, but pyridoxine derivatives are widely used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Photodegradable formulations should protect from light. May convert to pyridoxic acid on skin. Generally well-tolerated as a vitamin B6 vitamer.

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Concern Level: Low

Frequently Asked Questions

Is Pyridoxal safe in cosmetics?

Photodegradable formulations should protect from light. May convert to pyridoxic acid on skin. Generally well-tolerated as a vitamin B6 vitamer. The EU classifies Pyridoxal as "permitted". Safety rating: GOOD.

Is Pyridoxal allowed in the EU?

Pyridoxal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyridoxal do in cosmetics?

Pyridoxal functions as: Skin conditioning agent, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 66-72-8.

What is the Margin of Safety for Pyridoxal?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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