Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Hexanal. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1.05 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 95.6999969482 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Flammable Liquid Category 3 (GHS) classified H226; reactive aldehyde with potential skin irritant effects at high concentrations; must comply with IFRA Category limits
Regulatory Flags
Frequently Asked Questions
Is Hexanal safe in cosmetics?
Flammable Liquid Category 3 (GHS) classified H226; reactive aldehyde with potential skin irritant effects at high concentrations; must comply with IFRA Category limits The EU classifies Hexanal as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Hexanal allowed in the EU?
Hexanal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexanal do in cosmetics?
Hexanal functions as: Fragrance ingredient (Aldehyde C-6). It is classified as a cosmetic ingredient in our database. CAS number: 66-25-1.
What is the Margin of Safety for Hexanal?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hexanal?
The NOAEL (No Observed Adverse Effect Level) for Hexanal is 1.05 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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